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Journal Article

Potential Mechanisms of COX-2 Selective Inhibitors Affecting Cardiovascular Risk


Howard S. Smith

J Cancer Pain Symptom Palliation 2006;2(3):5-18

It appears that in COX-2 selective inhibitors may increase the risk of major adverse cardiovascular events. Various potential mechanisms are presented whereby COX-2 selective inhibitors may enhance the risk of cardiovascular events in certain patients. It is conceivable that different mechanisms may be involved in different circumstances and that multifactorial mechanisms may occasionally be operating in conjunction with one another.

[ DOI 10.1300/J427v02n03_02 resolve ]


 

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