Short- and long-term use of medication for psychological distress after the diagnosis of cancer

Support Care Cancer. 2017 Mar;25(3):757-768. doi: 10.1007/s00520-016-3456-z. Epub 2016 Oct 26.

Abstract

Purpose: This study investigated the short- and long-term use of medication for psychological distress after the diagnosis of cancer.

Methods: Longitudinal data from the Taiwan National Health Insurance database were used to follow 35,137 cancer patients for 2.5 years after being diagnosed in 2006 and 2007.

Results: Among those patients who survived for at least 180 days, 20.9 % had used psychotropic medications; sedatives were the most frequently prescribed (14.3 %), followed by antidepressants (5.5 %), anxiolytics (3.6 %), and antipsychotics (2.7 %). Lung cancer, prostate cancer, and oral cancer showed a significant association with the regular use of medication in the first 180 days. Among patients who survived for at least 2.5 years, 4.8 % still used psychotropic medication on a regular basis. Lung cancer and prostate cancer were associated with such prolonged use.

Conclusions: This longitudinal study found that the type of cancer was significantly associated with the use of psychotropic drugs after the diagnosis was made. It provided information about the trajectory of that use and found that a small number of patients were still using those medications after 2.5 years.

Keywords: Cancer; Long-term demand; Medication possession ratio; Psychological distress; Psychotropic medication.

MeSH terms

  • Aged
  • Drug Administration Schedule
  • Female
  • Humans
  • Hypnotics and Sedatives / administration & dosage
  • Longitudinal Studies
  • Male
  • Middle Aged
  • National Health Programs
  • Neoplasms / psychology*
  • Psychotropic Drugs / administration & dosage*
  • Retrospective Studies
  • Stress, Psychological / drug therapy*
  • Stress, Psychological / etiology
  • Stress, Psychological / psychology
  • Taiwan

Substances

  • Hypnotics and Sedatives
  • Psychotropic Drugs