Background. The authors report their own experience with percutaneous vertebroplasty. Percutaneous vertebroplasty is a technique which allows to inject acrylic surgical cement into the vertebral body. This is minimally invasive method indicated in treatment of certain spinal lesions affecting the vertebral bodies, as osteoporotic fractures, angiomas and focal neoplasms. <br /> Material and methods. Since October 1999 the authors treated 7 patients with angiomas of the vertebral bodies and 11 patients with spinal neoplasms. Cement injections were realized under local anesthesia.<br /> Results. In group of 7 cases with spinal metastases 3 patients declared important pain relief. All 7 patients with spinal angiomas declared no pain in follow-up. <br /> Conclusions. Percutaneous vertebroplasty is well-tolerated by patients. Filling by cement is efficace in treatment of vertebral angiomas. Filling of spinal neoplasmatic lesions result in palliative pain relief.